Tech Startups in Irvine
Every active Irvine startup we currently index, sorted by score and momentum.
About startups in Irvine
Irvine is home to 3 tech startups indexed on techstartupslist.com. This page lists every active Irvine company we track, with logos, taglines, and direct links to each company's site — no paywalled middleman. Notable Irvine startups in the index include afterfive, Entelexo Biotherapeutics, and Vena Vitals. Each profile surfaces team size, founding year, category, and any open roles their careers page is publicly scrapable for. The Irvine cohort leans toward Healthcare and Dev Tools, reflecting how the local startup ecosystem is concentrated. Recurring tags across these companies: SaaS, Consumer, Social, Biotech, Hard Tech. The directory's filter UI accepts any of them as a query. Y Combinator batches represented in Irvine: Sp26, W21, and S20. Jump to the per-batch landing pages for batch-specific cohort views. the listing refreshes whenever the scrape runs so this stays current as Irvine companies launch, raise, and ship. For roles open at these companies, see /jobs/location/irvine — every apply link goes to the company's own site, not an aggregator.
Five standout startups, five open roles, every Monday
A weekly digest pulled from the 5,200+ startups and 6,700+ jobs we track. No fluff, no resend.
Double opt-in. Unsubscribe anytime.
Frequently asked questions
How many tech startups are based in Irvine?
Our index currently tracks 3 active tech startups based in Irvine. New entries appear automatically as they're discovered through our scrapers; shutdowns are flagged inactive and hidden from this listing.
What are the top tech startups in Irvine?
Among the Irvine startups indexed here: afterfive, Entelexo Biotherapeutics, and Vena Vitals. Sorting prioritizes curated score and trending signals.
Where can I find startup jobs in Irvine?
Open roles at indexed Irvine startups appear on /jobs/location/irvine. Each role links directly to the company's official application page.
How often is the Irvine startup list updated?
Automated scrapers refresh this page on the same daily cadence as the rest of the directory. The last index update was 2026-09-02.