← Startups in San Francisco

San Francisco AI 572 startups

"AI" Startups in San Francisco

Every active San Francisco startup we index that carries the "AI" tag.

All startups in San Francisco → "AI" startups nationwide →

Last updated

2026-09-02

Hiring right now 5% 27 of 572

Open roles 570

City San Francisco

Our index currently lists 572 tech startups in San Francisco tagged "AI" — a city×tag slice of the live directory, not every "AI" company nationwide and not every San Francisco startup regardless of tag. 5% of this slice is hiring right now (27 of 572). Apply links on each profile go to the company's own site; we don't act as a middleman. "AI" startups in San Francisco include AfterQuery, Deepgram, Exa, Gigs, and Hightouch. Categories represented here: AI / ML, Healthcare, and Hardware. YC batches in this slice: S26, S24, W24, and Sp26, among others. Widen the view anytime: all San Francisco startups at /startups/location/san-francisco, or every "AI" company nationwide at /startups/tag/ai.

Applied research lab curating data solutions for foundation model…

Artificial IntelligenceB2BData Labeling

Building foundational AI for speech transcription and understanding.

AI-Enhanced LearningAPIAI

Web search rebuilt for LLMs

Developer ToolsSearchAI

The OS for Embedded Telecom

FintechHR TechAPI

The leading Composable CDP and AI Decisioning platform

MarketingEnterprise SoftwareAI

Reshaping industrial quality with AI, hardware, and software

Deep LearningIoTComputer Vision

The complete agentic document platform

DocumentsData EngineeringEnterprise Software

Supercharge Your Contact Center Operations with AI Phone Agents

Artificial IntelligenceAI

AI engine powering autonomous brands starting with gloglo.com

Consumer Health ServicesConsumerE-commerce

AI-native materials discovery powered by unpublished experimental data

Hard TechAdvanced MaterialsAI

Agent simulation and RL for researchers

AIOpsArtificial IntelligenceAPI

Open-source, AI-first and no-code business automation tool

Workflow AutomationOpen SourceNo-code

HardwareDesignAI

Real-time AI Compliance for Medical Documentation

Health TechB2BCompliance

Your AI Partner for SAP Development

Enterprise SoftwareAI

Affogato AI — Your Agent for instant TikToks, Reels, and ads.

Artificial IntelligenceGenerative AIAI

AI Agents that automate enterprise software processes

Reinforcement LearningEnterpriseAI

Context layer for production-grade AI agents

Artificial IntelligenceDeveloper ToolsOpen Source

AI sales prospecting. Replace your SDR with AiSDR

Artificial IntelligenceSaaSB2B

Autonomous Customer Operations

Artificial IntelligenceDeveloper ToolsB2B

Your AI recruiter for interviewing and identifying the best talent

SaaSB2BRecruiting

The company brain for construction companies

A dual-arm robot built for physical AI.

HardwareRoboticsManufacturing

High performance file system for agents

Developer ToolsMachine LearningBig Data

Autonomous organizations without humans in the loop

Machine LearningAI

Andromeda Surgical

Autonomous surgical robots

Hard TechMachine LearningMedical Robotics

Gen AI molecular simulations that reproduce wetlab results

AI-powered Drug DiscoveryArtificial IntelligenceBiotech

Continuous offensive security for the enterprise.

CybersecurityAI

voice-first hardware interface for human-agent interaction

HardwareConsumerAI

Your software should build itself.

Enterprise SoftwareInfrastructureAI

Frontier Voice Input - write 4x faster than typing.

Artificial IntelligenceConsumerProductivity

Aquarium Learning

We help ML teams improve their models by improving their datasets

Deep LearningDeveloper ToolsGenerative AI

Global payouts for the workforce powering AI

Crypto / Web3NeobankAI

The high-performance file system that connects AI to data

Developer ToolsMachine LearningBig Data

SaaSConstructionB2B

Lab working on long-horizon autonomous research and coding agents

Deep LearningGenerative AIMachine Learning

AI-native internal audit firm

Database sandboxes for Agents

Data EngineeringInfrastructureAI

AI receptionist for dentists

Artificial IntelligenceHealth TechDental

Improve how users experience your product through AI Agents

AI recruiters for staffing agencies

Artificial IntelligenceRecruitingAI

AI Coworkers for IT teams

SaaSEnterprise SoftwareAI

Automating open-ended research.

Artificial IntelligenceAI

AI advisor for retail investors

FintechInvestingConsumer Finance

Extensible, Integrated Technology that Simplifies Health Systems

SaaSHealth TechTelehealth

Ultra-precise AI weather forecasting.

Artificial IntelligenceMachine LearningWeather

AI Agents for Analog Circuit Design

Generative AIReinforcement LearningB2B

Infuse knowledge into language models with just 10 samples

AIOpsDeep LearningDeveloper Tools

Showing 48 of 572 Filter the directory by this slice →

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1 of 4 similar companies is hiring right now · most common: Founding

Deliver complete data analysis from a single question

Artificial IntelligenceAnalyticsData Engineering

The agentic quality platform for web and mobile

Artificial IntelligenceDeveloper ToolsB2B

Building the Operating System for B&M Retail using Deep Learning

Deep LearningGroceryComputer Vision

Robotic factories that build robots.

Deep LearningHardwareRobotics

All startups in San FranciscoEvery tag "AI" startups nationwideEvery city "Artificial Intelligence" startups in San Francisco606 startups "B2B" startups in San Francisco520 startups "SaaS" startups in San Francisco428 startups "Developer Tools" startups in San Francisco307 startups "Fintech" startups in San Francisco180 startups "Generative AI" startups in San Francisco137 startups "AI" startups in New York City132 startups "Consumer" startups in San Francisco120 startups

Frequently asked questions

How many "AI" startups are in San Francisco?

Our index currently tracks 572 active tech startups in San Francisco tagged "AI". Counts move as scrapers discover new companies and flag shutdowns inactive.

Which "AI" startups are based in San Francisco?

Companies on this page include AfterQuery, Deepgram, and Exa, plus 569 more below. Each profile links to the company's site and any open roles we scrape.

How is this different from the San Francisco startups page or the "AI" tag page?

/startups/location/san-francisco lists every indexed startup in San Francisco across tags. /startups/tag/ai lists every "AI" startup nationwide. This page is the intersection — only companies that resolve to both San Francisco and "AI".

Are these San Francisco "AI" startups hiring?

27 of the 572 companies on this page currently have open roles in our jobs index.

How often is this list updated?

Automated scrapers refresh on the same daily cadence as the rest of the directory. The last index update was 2026-09-02.