← Startups in San Francisco

San Francisco SaaS 428 startups

"SaaS" Startups in San Francisco

Every active San Francisco startup we index that carries the "SaaS" tag.

All startups in San Francisco → "SaaS" startups nationwide →

Last updated

2026-09-02

Hiring right now 7% 28 of 428

Open roles 1350

City San Francisco

Our index currently lists 428 tech startups in San Francisco tagged "SaaS" — a city×tag slice of the live directory, not every "SaaS" company nationwide and not every San Francisco startup regardless of tag. 7% of this slice is hiring right now (28 of 428). Apply links on each profile go to the company's own site; we don't act as a middleman. "SaaS" startups in San Francisco include Linear, Accord, Algolia, Benchling, and Fivetran. Categories represented here: AI / ML, Dev Tools, and Healthcare. YC batches in this slice: Sp26, W23, S21, and W22, among others. Widen the view anytime: all San Francisco startups at /startups/location/san-francisco, or every "SaaS" company nationwide at /startups/tag/saas.

The issue tracker built for high-performance teams.

SaaSDev ToolsProject Management

The Revenue Excellence Platform

A developer-friendly and enterprise-grade search API.

Developer ToolsSaaSB2B

Unlocking the power of biotech with modern software for modern science

The leader in automated data movement

SaaSB2BAnalytics

Platform for global logistics.

SaaSLogisticsSupply Chain

A single API for all your integrations

Developer ToolsSaaSOpen Source

We automate operations for hospitals and health systems

Artificial IntelligenceSaaSDigital Health

Economic infrastructure for the internet.

Banking as a ServiceFintechSaaS

Transforming how health systems optimize labor

SaaSB2BHealthcare

Professional website design and publishing platform.

SaaSDesignMarketing

The easiest way to automate your work.

SaaSB2BAutomation

Collaborative workspace for patent litigators

SaaSB2BLegalTech

The AI-native platform for next-generation protein characterization.

Artificial IntelligenceSaaSB2B

Analytics stack for omnichannel retailers and brands

SaaSAnalyticsRetail

The AI career platform for healthcare workers

Artificial IntelligenceMarketplaceSaaS

AI Affiliate Network For Financial Companies

Artificial IntelligenceSaaSB2B

AI Financial Operations for Construction

SaaSConstructionB2B

AI sales prospecting. Replace your SDR with AiSDR

Artificial IntelligenceSaaSB2B

The Github For Coding Agents

Artificial IntelligenceGenerative AISaaS

AI-powered image analysis for life sciences

AI-powered Drug DiscoveryMachine LearningSaaS

Your AI recruiter for interviewing and identifying the best talent

SaaSB2BRecruiting

The health coach that texts you first

SaaSHealth TechDigital Health

Faster clinical documentation for home health nurses

Artificial IntelligenceSaaSHealth Tech

AI-Powered Product Data Enrichment

Artificial IntelligenceMachine LearningSaaS

Apptimize lets mobile teams innovate faster to create an amazing user…

SaaSConstructionB2B

Real-world sandboxes to test agents and agent-facing software

Developer ToolsSaaSInfrastructure

Medical coding automation

SaaSHealth TechB2B

Cloud-native stream processing

Developer ToolsSaaSOpen Source

A search technology that actually finds what you’re looking for.

Artificial IntelligenceMachine LearningSaaS

Software that streams data from databases to warehouses in real-time

Developer ToolsSaaSData Engineering

AI order entry for food distributors: emails and texts to ERP

SaaSFood & Beverage

The browser built to do real work for you

Artificial IntelligenceSaaSAutomation

Developer ToolsSaaS

AI Coworkers for IT teams

SaaSEnterprise SoftwareAI

AI Operating System for Clinical Development

Artificial IntelligenceSaaSHealth Tech

Extensible, Integrated Technology that Simplifies Health Systems

SaaSHealth TechTelehealth

Modern customer support platform replacement for Intercom and Zendesk

SaaSB2BCustomer Success

Modernizing global transportation payments.

FintechSaaSPayments

One-Stop Shop for Convenience Store Inventory

MarketplaceSaaSB2B

Datadog for industrial robots

HardwareRobotic Process AutomationSaaS

Google-level engineering productivity suite

Developer ToolsSaaSB2B

The only end-to-end crowdfunding platform built for today’s creators

SaaSCrowdfunding

BackType was an analytics company acquired by Twitter in 2011

SaaSData Engineering

Bandit ML builds machine learning tools for e-commerce companies.

Machine LearningSaaSE-commerce

An AI-powered, all-in-one business platform for content creators

One chat app to rule them all

Showing 48 of 428 Filter the directory by this slice →

Weekly digest

A weekly digest pulled from the 5,200+ startups and 6,700+ jobs we track. No fluff, no resend.

Double opt-in. Unsubscribe anytime.

2 of 4 similar companies are hiring right now · most common: Engineering

Build in a weekend. Scale to millions.

Developer ToolsOpen SourceBig Data

Medical language models to automate healthcare operations

Artificial IntelligenceB2BHealthcare

The Agentic ERP for supply chain operations

B2BLogisticsSupply Chain

The open source Postman alternative.

Developer ToolsOpen SourceAPI

All startups in San FranciscoEvery tag "SaaS" startups nationwideEvery city "Artificial Intelligence" startups in San Francisco606 startups "AI" startups in San Francisco572 startups "B2B" startups in San Francisco520 startups "Developer Tools" startups in San Francisco307 startups "Fintech" startups in San Francisco180 startups "Generative AI" startups in San Francisco137 startups "SaaS" startups in New York City125 startups "Consumer" startups in San Francisco120 startups

Frequently asked questions

How many "SaaS" startups are in San Francisco?

Our index currently tracks 428 active tech startups in San Francisco tagged "SaaS". Counts move as scrapers discover new companies and flag shutdowns inactive.

Which "SaaS" startups are based in San Francisco?

Companies on this page include Linear, Accord, and Algolia, plus 425 more below. Each profile links to the company's site and any open roles we scrape.

How is this different from the San Francisco startups page or the "SaaS" tag page?

/startups/location/san-francisco lists every indexed startup in San Francisco across tags. /startups/tag/saas lists every "SaaS" startup nationwide. This page is the intersection — only companies that resolve to both San Francisco and "SaaS".

Are these San Francisco "SaaS" startups hiring?

28 of the 428 companies on this page currently have open roles in our jobs index.

How often is this list updated?

Automated scrapers refresh on the same daily cadence as the rest of the directory. The last index update was 2026-09-02.