← Startups in San Francisco

San Francisco Automation 62 startups

"Automation" Startups in San Francisco

Every active San Francisco startup we index that carries the "Automation" tag.

All startups in San Francisco → "Automation" startups nationwide →

Last updated

2026-09-02

Hiring right now 2% 1 of 62

Open roles 7

City San Francisco

Our index currently lists 62 tech startups in San Francisco tagged "Automation" — a city×tag slice of the live directory, not every "Automation" company nationwide and not every San Francisco startup regardless of tag. 2% of this slice is hiring right now (1 of 62). Apply links on each profile go to the company's own site; we don't act as a middleman. "Automation" startups in San Francisco include Zapier, Alchemy, Almond, Artisan, and Aside. Categories represented here: AI / ML, Hardware, and Productivity. YC batches in this slice: Sp26, S26, W24, and W23, among others. Widen the view anytime: all San Francisco startups at /startups/location/san-francisco, or every "Automation" company nationwide at /startups/tag/automation.

The easiest way to automate your work.

SaaSB2BAutomation

AI-powered image analysis for life sciences

AI-powered Drug DiscoveryMachine LearningSaaS

A dual-arm robot built for physical AI.

HardwareRoboticsManufacturing

The AI BDR for enterprise revenue teams, plus a full AI sales team

Artificial IntelligenceB2BSales

The browser built to do real work for you

Artificial IntelligenceSaaSAutomation

The integration layer for healthcare: EHRs, payer portals & more

Artificial IntelligenceRobotic Process AutomationHealth Tech

Desktop RPA with AI computer use

Artificial IntelligenceDeep LearningB2B

AI enabled RPA using ChatGPT and computer vision

DocumentsArtificial IntelligenceDeveloper Tools

AutoPallet Robotics

We make robots that move boxes in warehouses

Hard TechMachine LearningWarehouse Management Tech

AI agents reliable enough to do real work

Artificial IntelligenceProductivityEnterprise

Constellations as a Service

SatellitesAerospaceAutomation

AI agents for insurance claims

Artificial IntelligenceInsuranceNo-code

Agentic supply chain optimization

Artificial IntelligenceManufacturingAutomation

Leading open-source web agent project with 50k stars in 3 months

Artificial IntelligenceOpen SourceAPI

Operating system for premium professional communities

Artificial IntelligenceAutomationOperations

Effortless AI automation for business operations

AIOpsB2BAutomation

AI Teammate to Enable Every Knowledge Worker to Be a Top Performer

ProductivityBig DataAutomation

Discover the photos and videos people are taking of your brand or…

Social MediaMarketingAutomation

Clara is a human-in-the-loop assistant that helps automate repetitive…

AI Coworkers for Business Automation

Artificial IntelligenceB2BWorkflow Automation

Agents for Industrial Supply Chains

AIOpsLogisticsSupply Chain

AI that updates your CRM for you

Artificial IntelligenceCRMAutomation

Autonomous services for humanity.

Robotic Process AutomationRoboticsAutomation

AI that audits AI — catching hallucinations before you ship them.

ProductivityBig DataEnterprise Software

Where drug teams run their entire program, discovery to FDA approval

Artificial IntelligenceSaaSB2B

Find & resolve issues in data center engineering & operations using AI

Artificial IntelligenceAerospaceEnterprise Software

Getting creators more deals

B2BSocial MediaAutomation

The AI fraud hunter

ComplianceEnterpriseAutomation

FollowUpThen is an email-based personal assistant that sends you…

ProductivityAutomationAI

AI Creative Strategist

Artificial IntelligenceSaaSAnalytics

Control lab instruments with natural language.

The AI-Native Decision Layer for Health Insurance

Health TechHealthcareInsurance

Generate fast, reliable APIs for any platform

Developer ToolsB2BAPI

The AI-Native CRM that works for you

B2BCRMAutomation

Automatic circuit board design.

The E2E testing layer for AI-driven development

Artificial IntelligenceDeveloper ToolsB2B

Open source mobile marketing platform. Alternative to appcues /…

SaaSB2BOpen Source

Workflow automation, without AI hallucinations.

AI-Enhanced LearningWorkflow AutomationAutomation

Reimagining how Machines Learn

AIOpsArtificial IntelligenceDeveloper Tools

Program computers with natural language

Generative AIConsumerProductivity

Reliable Web Agents for Enterprise

Developer ToolsAutomationAI

Live alerts for anything happening in the world.

Artificial IntelligenceB2BAutomation

AI Agents for Commercial Lending

DocumentsFinanceAutomation

Agentic operating system for auto repair shops

SaaSWorkflow AutomationAutomation

We make law firms AI-native.

Artificial IntelligenceB2BLegal

communication for agents

Developer ToolsAutomationEmail

Autonomous manufacturing for mechanical parts

HardwareManufacturingAutomation

AI documentation engineer – test & autoimprove stale product docs

Artificial IntelligenceDeveloper ToolsB2B

Showing 48 of 62 Filter the directory by this slice →

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Self learning computer use agent for developers

Artificial IntelligenceDeveloper ToolsRobotic Process Automation

The relationship intelligence platform for enterprise revenue

Artificial IntelligenceSaaSB2B

The Robot Learning Company

Tools for the next era of physical automation.

Machine LearningRobotics

Gemnote is the easiest way to design, create and send custom products.

E-commerceCustomization

All startups in San FranciscoEvery tag "Automation" startups nationwideEvery city "Artificial Intelligence" startups in San Francisco606 startups "AI" startups in San Francisco572 startups "B2B" startups in San Francisco520 startups "SaaS" startups in San Francisco428 startups "Developer Tools" startups in San Francisco307 startups "Fintech" startups in San Francisco180 startups "Generative AI" startups in San Francisco137 startups "Consumer" startups in San Francisco120 startups

Frequently asked questions

How many "Automation" startups are in San Francisco?

Our index currently tracks 62 active tech startups in San Francisco tagged "Automation". Counts move as scrapers discover new companies and flag shutdowns inactive.

Which "Automation" startups are based in San Francisco?

Companies on this page include Zapier, Alchemy, and Almond, plus 59 more below. Each profile links to the company's site and any open roles we scrape.

How is this different from the San Francisco startups page or the "Automation" tag page?

/startups/location/san-francisco lists every indexed startup in San Francisco across tags. /startups/tag/automation lists every "Automation" startup nationwide. This page is the intersection — only companies that resolve to both San Francisco and "Automation".

Are these San Francisco "Automation" startups hiring?

1 of the 62 companies on this page currently have open roles in our jobs index.

How often is this list updated?

Automated scrapers refresh on the same daily cadence as the rest of the directory. The last index update was 2026-09-02.