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San Francisco Infrastructure 94 startups

"Infrastructure" Startups in San Francisco

Every active San Francisco startup we index that carries the "Infrastructure" tag.

All startups in San Francisco → "Infrastructure" startups nationwide →

Last updated

2026-09-02

Hiring right now 4% 4 of 94

Open roles 87

City San Francisco

Our index currently lists 94 tech startups in San Francisco tagged "Infrastructure" — a city×tag slice of the live directory, not every "Infrastructure" company nationwide and not every San Francisco startup regardless of tag. 4% of this slice is hiring right now (4 of 94). Apply links on each profile go to the company's own site; we don't act as a middleman. "Infrastructure" startups in San Francisco include Alpaca, Aden, Akkari, Amulet, and Approxima. Categories represented here: AI / ML, Dev Tools, and Infrastructure. YC batches in this slice: S26, Sp26, S24, and S25, among others. Widen the view anytime: all San Francisco startups at /startups/location/san-francisco, or every "Infrastructure" company nationwide at /startups/tag/infrastructure.

API-first stock and crypto brokerage platform

Developer ToolsFintechAPI

Open source agent generation framework

Artificial IntelligenceDeveloper ToolsInfrastructure

Autonomous Customer Operations

Artificial IntelligenceDeveloper ToolsB2B

High performance file system for agents

Developer ToolsMachine LearningBig Data

Your software should build itself.

Enterprise SoftwareInfrastructureAI

API sandboxes, built for AI agents

Artificial IntelligenceDeveloper ToolsAPI

The high-performance file system that connects AI to data

Developer ToolsMachine LearningBig Data

Database sandboxes for Agents

Data EngineeringInfrastructureAI

Real-world sandboxes to test agents and agent-facing software

Developer ToolsSaaSInfrastructure

Faster builds, zero effort.

Developer ToolsInfrastructure

Infuse knowledge into language models with just 10 samples

AIOpsDeep LearningDeveloper Tools

The human-in-the-loop system for robots

Hard TechRoboticsInfrastructure

The easiest way to make private AI models

Machine LearningInfrastructure

The perpetual sandbox platform

Artificial IntelligenceDeveloper ToolsCloud Computing

The brand layer for agents.

MarketingInfrastructureAI

Accurate, high-performance retrieval for AI agents

B2BAPIData Engineering

Research services for ChatGPT and Claude

Artificial IntelligenceAPIInfrastructure

The Agent Control Plane for IT teams

B2BInfrastructureAI

Acquired by Brex. Building digital payments infrastructure.

PaymentsInfrastructure

All-in-one platform to create AI agents with your private knowledge

SaaSInfrastructureAI

Building agents that reads logs and fixes issues on your behalf.

Artificial IntelligenceInfrastructure

Turn any website into an API.

Developer ToolsInfrastructure

Unlock wasted GPU capacity.

Deep LearningB2BInfrastructure

Experiential Labs

Open source OpenRouter that turns your traffic into a better model

Reinforcement LearningInfrastructureAI

Agentic AI Security and Governance

Artificial IntelligenceDeveloper ToolsSecurity

Autoresearch as a service: we solve your hardest measurable problems

Artificial IntelligenceDeveloper ToolsMachine Learning

Real-world training data for frontier AI labs and robotics.

RoboticsCrowdsourcingBig Data

Open-source, dev-friendly observability.

Developer ToolsSaaSB2B

The COLD Task Framework

AIOpsDeveloper ToolsCloud Computing

The identity and communication layer for AI agents

Developer ToolsInfrastructureAI

The agent-native AWS

Developer ToolsOpen SourceInfrastructure

Crazy fast, open source infra for AI agents to use the Internet

Developer ToolsCloud ComputingInfrastructure

AI Agents for Platform Engineering

AIOpsDeveloper ToolsDevOps

Lambda Robotics

Robotics for AI Infrastructure

RoboticsInfrastructureAI

Near-real-time video infrastructure for LLMs

ConsumerB2BVideo

Production Monitoring for AI agents

Artificial IntelligenceDeveloper ToolsB2B

We automatically monetize idle GPUs

Artificial IntelligenceMachine LearningCloud Computing

The Localization Engineering Platform

Developer ToolsB2BInternational

AI CAD Software for Civil Engineering

Machine LearningComputer VisionDesign Tools

Code with local models, zero setup

Artificial IntelligenceDeveloper ToolsOpen Source

Cloud infrastructure for MCP servers and Claude / ChatGPT apps.

Developer ToolsB2BOpen Source

The managed cloud for AI agents.

Developer ToolsCloud ComputingInfrastructure

The Memory layer for AI Agents

Developer ToolsGenerative AIOpen Source

Build production-ready apps with AI

Artificial IntelligenceDeveloper ToolsInfrastructure

Continual Learning for Agents

Reinforcement LearningB2BInfrastructure

Turn AI adoption into a recurring revenue line.

Generative AIB2BNo-code

Unified Agent Infrastructure

Artificial IntelligenceInfrastructure

Transform any software to multi-cloud SaaS in minutes not years

Developer ToolsSaaSB2B

Showing 48 of 94 Filter the directory by this slice →

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1 of 4 similar companies is hiring right now · most common: Engineering

iMessage infrastructure for business

Artificial IntelligenceSaaSAPI

Stablecoin API for global payments

Developer ToolsFintechCrypto / Web3

Autonomous operations for industrial distributors

B2BWorkflow AutomationSupply Chain

Build in a weekend. Scale to millions.

Developer ToolsOpen SourceBig Data

All startups in San FranciscoEvery tag "Infrastructure" startups nationwideEvery city "Artificial Intelligence" startups in San Francisco606 startups "AI" startups in San Francisco572 startups "B2B" startups in San Francisco520 startups "SaaS" startups in San Francisco428 startups "Developer Tools" startups in San Francisco307 startups "Fintech" startups in San Francisco180 startups "Generative AI" startups in San Francisco137 startups "Consumer" startups in San Francisco120 startups

Frequently asked questions

How many "Infrastructure" startups are in San Francisco?

Our index currently tracks 94 active tech startups in San Francisco tagged "Infrastructure". Counts move as scrapers discover new companies and flag shutdowns inactive.

Which "Infrastructure" startups are based in San Francisco?

Companies on this page include Alpaca, Aden, and Akkari, plus 91 more below. Each profile links to the company's site and any open roles we scrape.

How is this different from the San Francisco startups page or the "Infrastructure" tag page?

/startups/location/san-francisco lists every indexed startup in San Francisco across tags. /startups/tag/infrastructure lists every "Infrastructure" startup nationwide. This page is the intersection — only companies that resolve to both San Francisco and "Infrastructure".

Are these San Francisco "Infrastructure" startups hiring?

4 of the 94 companies on this page currently have open roles in our jobs index.

How often is this list updated?

Automated scrapers refresh on the same daily cadence as the rest of the directory. The last index update was 2026-09-02.