← Startups in San Francisco

San Francisco Machine Learning 114 startups

"Machine Learning" Startups in San Francisco

Every active San Francisco startup we index that carries the "Machine Learning" tag.

All startups in San Francisco → "Machine Learning" startups nationwide →

Last updated

2026-09-02

Hiring right now 4% 5 of 114

Open roles 161

City San Francisco

Our index currently lists 114 tech startups in San Francisco tagged "Machine Learning" — a city×tag slice of the live directory, not every "Machine Learning" company nationwide and not every San Francisco startup regardless of tag. 4% of this slice is hiring right now (5 of 114). Apply links on each profile go to the company's own site; we don't act as a middleman. "Machine Learning" startups in San Francisco include LanceDB, TRM Labs, 1stCollab, 64x Bio, and Abalone Bio. Categories represented here: AI / ML, Healthcare, and Dev Tools. YC batches in this slice: S26, S24, S21, and W22, among others. Widen the view anytime: all San Francisco startups at /startups/location/san-francisco, or every "Machine Learning" company nationwide at /startups/tag/machine-learning.

Open-source, serverless vectordb for production-scale generative AI

AIOpsMachine LearningOpen Source

TRM is building a safer world for billions of people.

FintechMachine LearningGovTech

Performance-Optimized Influencer Marketing at Scale

Artificial IntelligenceMachine LearningMarketing

Enabling next generation medicines. A comprehensive platform and…

Gene TherapyMachine Learning

We create activating antibodies to treat diseases others can’t.

Machine LearningSynthetic BiologyTherapeutics

Predictive analytics and clinical pathways for hospitals

Machine LearningHealthcare

AI-powered image analysis for life sciences

AI-powered Drug DiscoveryMachine LearningSaaS

High performance file system for agents

Developer ToolsMachine LearningBig Data

Autonomous organizations without humans in the loop

Machine LearningAI

Andromeda Surgical

Autonomous surgical robots

Hard TechMachine LearningMedical Robotics

AI-Powered Product Data Enrichment

Artificial IntelligenceMachine LearningSaaS

Aquarium Learning

We help ML teams improve their models by improving their datasets

Deep LearningDeveloper ToolsGenerative AI

The high-performance file system that connects AI to data

Developer ToolsMachine LearningBig Data

Lab working on long-horizon autonomous research and coding agents

Deep LearningGenerative AIMachine Learning

A search technology that actually finds what you’re looking for.

Artificial IntelligenceMachine LearningSaaS

Robotic pitstops for self-driving cars

Artificial IntelligenceHardwareMachine Learning

Ultra-precise AI weather forecasting.

Artificial IntelligenceMachine LearningWeather

AutoPallet Robotics

We make robots that move boxes in warehouses

Hard TechMachine LearningWarehouse Management Tech

Bandit ML builds machine learning tools for e-commerce companies.

Machine LearningSaaSE-commerce

The easiest way to make private AI models

Machine LearningInfrastructure

Restaurant Loyalty Using Quiz

Generative AIMachine LearningHuman Resources

An Operating System for agriculture.

Machine LearningMarketplaceAnalytics

Your voice. Your health. We care.

HardwareMachine LearningConsumer Health Services

Autonomous freight coordination

Machine LearningWorkflow AutomationLogistics

Make Banking Magical

Artificial IntelligenceConversational BankingFintech

The video context layer for AI.

Developer ToolsMachine LearningVideo

The biggest crowdsourced benchmark for Computer-Use

AIOpsArtificial IntelligenceMachine Learning

Automating Healthcare Revenue Cycle Management with AI Workforce

Artificial IntelligenceMachine LearningHealthcare

Conductor Quantum

AI that operates quantum computers for scientific discovery

Artificial IntelligenceHard TechMachine Learning

CrowdAI is the world's leading no-code platform for vision AI

Machine LearningComputer Vision

Self-driving cars.

Autonomous DeliveryMachine LearningClimate

Early detection of Alzheimer's disease

Artificial IntelligenceMachine LearningHealth Tech

Robots, parts & RL environments - delivered in 72 hrs or pickup in SF.

Artificial IntelligenceMachine LearningRobotics

DeepAware AI (Robotics Center of Silicon Valley)

Robots, parts & RL envs & evals - delivered in 48 hrs / pickup in SF.

Artificial IntelligenceMachine LearningRobotics

A better data science notebook.

Developer ToolsMachine Learning

Real-world data network for robots & world models

Artificial IntelligenceHardwareMachine Learning

Generative AI for administrative automation in healthcare

Generative AIMachine LearningHealth Tech

Generative AI for protein design

AI-powered Drug DiscoveryDeep LearningGenerative AI

Product recommendations.

Artificial IntelligenceMachine LearningRecommendation System

Pocket-sized AI cameras that catch asset damage.

Artificial IntelligenceHardwareMachine Learning

Compliant-Ready AI for the Enterprise

Machine LearningPrivacyData Engineering

Edwin is virtual English tutor - an AI-powered service for learning…

AI-Enhanced LearningEducationMachine Learning

Procure the right software 5x faster

Machine LearningSaaSB2B

Forward-deployed AI Agents

Artificial IntelligenceDeveloper ToolsMachine Learning

Autoresearch as a service: we solve your hardest measurable problems

Artificial IntelligenceDeveloper ToolsMachine Learning

We Rent Your Property by the Room. You earn 50% more Rent.

Machine LearningReal EstateProptech

Humanloop is the LLM evals platform for enterprises.

Generative AIMachine LearningSaaS

A Cloud-Based Bioinformatics and AI Platform

Machine LearningBiotechAnalytics

Showing 48 of 114 Filter the directory by this slice →

Weekly digest

A weekly digest pulled from the 5,200+ startups and 6,700+ jobs we track. No fluff, no resend.

Double opt-in. Unsubscribe anytime.

1 of 4 similar companies is hiring right now · most common: Engineering

Build in a weekend. Scale to millions.

Developer ToolsOpen SourceBig Data

Serverless Analytics on Postgres

Developer ToolsAnalyticsOpen Source

Creator marketing that scales like paid ads

MarketingAdvertisingCreator Economy

The AI performance marketing agent for entrepreneurs and growth teams

Artificial IntelligenceB2BMarketing

All startups in San FranciscoEvery tag "Machine Learning" startups nationwideEvery city "Artificial Intelligence" startups in San Francisco606 startups "AI" startups in San Francisco572 startups "B2B" startups in San Francisco520 startups "SaaS" startups in San Francisco428 startups "Developer Tools" startups in San Francisco307 startups "Fintech" startups in San Francisco180 startups "Generative AI" startups in San Francisco137 startups "Consumer" startups in San Francisco120 startups

Frequently asked questions

How many "Machine Learning" startups are in San Francisco?

Our index currently tracks 114 active tech startups in San Francisco tagged "Machine Learning". Counts move as scrapers discover new companies and flag shutdowns inactive.

Which "Machine Learning" startups are based in San Francisco?

Companies on this page include LanceDB, TRM Labs, and 1stCollab, plus 111 more below. Each profile links to the company's site and any open roles we scrape.

How is this different from the San Francisco startups page or the "Machine Learning" tag page?

/startups/location/san-francisco lists every indexed startup in San Francisco across tags. /startups/tag/machine-learning lists every "Machine Learning" startup nationwide. This page is the intersection — only companies that resolve to both San Francisco and "Machine Learning".

Are these San Francisco "Machine Learning" startups hiring?

5 of the 114 companies on this page currently have open roles in our jobs index.

How often is this list updated?

Automated scrapers refresh on the same daily cadence as the rest of the directory. The last index update was 2026-09-02.