← Startups in San Francisco

San Francisco Hard Tech 61 startups

"Hard Tech" Startups in San Francisco

Every active San Francisco startup we index that carries the "Hard Tech" tag.

All startups in San Francisco → "Hard Tech" startups nationwide →

Last updated

2026-09-02

Hiring right now 0% 0 of 61

Open roles 0

City San Francisco

Our index currently lists 61 tech startups in San Francisco tagged "Hard Tech" — a city×tag slice of the live directory, not every "Hard Tech" company nationwide and not every San Francisco startup regardless of tag. 0% of this slice is hiring right now (0 of 61). Apply links on each profile go to the company's own site; we don't act as a middleman. "Hard Tech" startups in San Francisco include 1849 bio, 83 Sciences, AirMyne, Andromeda Surgical, and Applied Electrodynamics, Inc.. Categories represented here: AI / ML, Hardware, and Industrials. YC batches in this slice: S26, Sp26, S24, and Sp25, among others. Widen the view anytime: all San Francisco startups at /startups/location/san-francisco, or every "Hard Tech" company nationwide at /startups/tag/hard-tech.

Engineering microbes for miners to unlock billions in trapped metal

Hard TechSynthetic BiologyBiotech

AI-native materials discovery powered by unpublished experimental data

Hard TechAdvanced MaterialsAI

Building systems to remove carbon dioxide from air at industrial scale

Carbon Capture and RemovalHard TechHardware

Andromeda Surgical

Autonomous surgical robots

Hard TechMachine LearningMedical Robotics

Applied Electrodynamics, Inc.

A new kind of camera that can see through walls.

Hard TechHardwareConstruction

Arlo Industries

Track drones and missiles without radars - Accurate, Passive, Scalable

Hard TechHardwareDefense

Gigascale Nanomanufacturing

Hard Tech3D PrintingSemiconductors

Neurostimulation implant to restore hearing & speech understanding

Hard TechNeurotechnologyHealth Tech

AutoPallet Robotics

We make robots that move boxes in warehouses

Hard TechMachine LearningWarehouse Management Tech

The human-in-the-loop system for robots

Hard TechRoboticsInfrastructure

AI chips for ultra-fast training and inference

Hard TechSemiconductorsAI

Low-latency AI engine for mobile devices & wearables

Artificial IntelligenceDeveloper ToolsHard Tech

Commercial alternative to the Deep Space Network

Hard TechHardwareSaaS

Conductor Quantum

AI that operates quantum computers for scientific discovery

Artificial IntelligenceHard TechMachine Learning

Cosmic Robotics

Autonomous construction on Earth and beyond

Hard TechRoboticsConstruction

AI-native test infrastructure to accelerate hardware companies.

Satellites for Manufacturing in Space

Unified flight software and hardware for the mission of tomorrow

Hard TechDronesSatellites

General Aviation

Fix ATC by connecting aircraft to the internet

Hard TechSatellitesTransportation

AI Physics Engine to replace simulations and prototypes

Artificial IntelligenceHard TechHardware

Hermes Robotics

Autonomous street sweeping as a service by retro-fitting vehicles

Autonomous TruckingHard TechRobotics

Building intellectually curious AI

Deep LearningHard TechAI

Industrial Next

Tesla autonomous manufacturing for everyone

Hard TechRoboticsManufacturing

InLoop Robotics

Robotic arms that pick and pack your orders.

Hard TechRoboticsLogistics

Personal AI Robots

Artificial IntelligenceDeveloper ToolsHard Tech

Robotic crews for large-scale infrastructure construction

Hard TechRoboticsConstruction

Robots with soul

Hard TechHardwareRobotics

Maquoketa Research

The intelligence layer for drones

Hard TechHardwareDrones

Maritime Fusion

Fusion reactors for ships

Fusion EnergyHard TechEnergy

Drones that clear clouds over solar farms and weaken hurricanes

Hard TechRenewable EnergyClimateTech

World models that train and test robots in sim, #1 on Physics-IQ

Hard TechRoboticsVirtual Reality

We build and operate underwater data centers.

Artificial IntelligenceHard TechHardware

Building robots to automate wetlabs

Hard TechRoboticsB2B

RF test equipment for next-gen spacecraft, drones, and cellphones

Hard TechAerospaceTelecommunications

American Humanoid which costs 3% of the competition

Hard TechHardwareRobotics

iPhone-based driver monitoring for commercial fleets.

Autonomous TruckingHard TechMachine Learning

AI performance monitoring for factory workers

Hard TechComputer VisionManufacturing

The Networking Layer of AI

Artificial IntelligenceHard TechHardware

Polymath Robotics

General Autonomy for Industrial Vehicles

Hard TechMachine LearningRobotics

AI for product formulation

Generative AIHard TechB2B

Turns every company into a data vendor

Hard TechReinforcement LearningRobotic Process Automation

Praxis Robotics

Turns every company into a data vendor

Hard TechReinforcement LearningRobotic Process Automation

Smart ring digital wallet

Hard TechHardwareConsumer

Automating nutrition tracking.

Artificial IntelligenceHard TechComputer Vision

Real-world evals for robots

Artificial IntelligenceHard TechHardware

Roin Technologies

Building robots to automate commercial concrete construction.

Hard TechHardwareRobotics

Helping AI understand the physical world

Hard TechHardwareEnterprise

The Cursor for Chip Design - Delivering Silicon-Ready Chip Designs…

Hard TechHardwareB2B

Showing 48 of 61 Filter the directory by this slice →

Weekly digest

A weekly digest pulled from the 5,200+ startups and 6,700+ jobs we track. No fluff, no resend.

Double opt-in. Unsubscribe anytime.

Shinkei Systems

Robots for longer-lasting, better-tasting fish at scale.

HardwareRoboticsFood Tech

We make carbon negative roads

Carbon Capture and RemovalConstructionClimate

Submarine drones for defense

HardwareSwarm AIRobotics

Tenet Industries

Low-cost, mass-producible defense systems

HardwareManufacturingDefense

All startups in San FranciscoEvery tag "Hard Tech" startups nationwideEvery city "Artificial Intelligence" startups in San Francisco606 startups "AI" startups in San Francisco572 startups "B2B" startups in San Francisco520 startups "SaaS" startups in San Francisco428 startups "Developer Tools" startups in San Francisco307 startups "Fintech" startups in San Francisco180 startups "Generative AI" startups in San Francisco137 startups "Consumer" startups in San Francisco120 startups

Frequently asked questions

How many "Hard Tech" startups are in San Francisco?

Our index currently tracks 61 active tech startups in San Francisco tagged "Hard Tech". Counts move as scrapers discover new companies and flag shutdowns inactive.

Which "Hard Tech" startups are based in San Francisco?

Companies on this page include 1849 bio, 83 Sciences, and AirMyne, plus 58 more below. Each profile links to the company's site and any open roles we scrape.

How is this different from the San Francisco startups page or the "Hard Tech" tag page?

/startups/location/san-francisco lists every indexed startup in San Francisco across tags. /startups/tag/hard-tech lists every "Hard Tech" startup nationwide. This page is the intersection — only companies that resolve to both San Francisco and "Hard Tech".

Are these San Francisco "Hard Tech" startups hiring?

0 of the 61 companies on this page currently have open roles in our jobs index.

How often is this list updated?

Automated scrapers refresh on the same daily cadence as the rest of the directory. The last index update was 2026-09-02.